Notable epigenetic role of hyperhomocysteinemia in atherogenesis
نویسندگان
چکیده
منابع مشابه
Epigenetic regulation of aortic remodeling in hyperhomocysteinemia.
Hyperhomocysteinemia (HHcy) is prevalent in patients with hypertension and is an independent risk factor for aortic pathologies. HHcy is known to cause an imbalance between matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs), leading to the accumulation of collagen in the aorta and resulting in stiffness and development of hypertension. Although the exact mechan...
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ژورنال
عنوان ژورنال: Lipids in Health and Disease
سال: 2014
ISSN: 1476-511X
DOI: 10.1186/1476-511x-13-134